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Protection Against Epithelial Damage During Candida albicans Infection Is Mediated by PI3K/Akt and Mammalian Target of Rapamycin Signaling

Background. The ability of epithelial cells (ECs) to discriminate between commensal and pathogenic microbes is essential for healthy living. Key to these interactions are mucosal epithelial responses to pathogen-induced damage. Methods. Using reconstituted oral epithelium, we assessed epithelial gen...

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Detalles Bibliográficos
Autores principales: Moyes, David L., Shen, Chengguo, Murciano, Celia, Runglall, Manohursingh, Richardson, Jonathan P., Arno, Matthew, Aldecoa-Otalora, Estibaliz, Naglik, Julian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017362/
https://www.ncbi.nlm.nih.gov/pubmed/24357630
http://dx.doi.org/10.1093/infdis/jit824