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Visualizing Dermal Permeation of Sodium Channel Modulators by Mass Spectrometric Imaging

[Image: see text] Determining permeability of a given compound through human skin is a principal challenge owing to the highly complex nature of dermal tissue. We describe the application of an ambient mass spectrometry imaging method for visualizing skin penetration of sodium channel modulators, in...

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Detalles Bibliográficos
Autores principales: Eberlin, Livia S., Mulcahy, John V., Tzabazis, Alexander, Zhang, Jialing, Liu, Huwei, Logan, Matthew M., Roberts, Heather J., Lee, Gordon K., Yeomans, David C., Du Bois, Justin, Zare, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017602/
https://www.ncbi.nlm.nih.gov/pubmed/24708172
http://dx.doi.org/10.1021/ja501635u