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Visualizing Dermal Permeation of Sodium Channel Modulators by Mass Spectrometric Imaging
[Image: see text] Determining permeability of a given compound through human skin is a principal challenge owing to the highly complex nature of dermal tissue. We describe the application of an ambient mass spectrometry imaging method for visualizing skin penetration of sodium channel modulators, in...
Autores principales: | Eberlin, Livia S., Mulcahy, John V., Tzabazis, Alexander, Zhang, Jialing, Liu, Huwei, Logan, Matthew M., Roberts, Heather J., Lee, Gordon K., Yeomans, David C., Du Bois, Justin, Zare, Richard N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017602/ https://www.ncbi.nlm.nih.gov/pubmed/24708172 http://dx.doi.org/10.1021/ja501635u |
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