Cargando…
Coupled Folding and Binding of the Disordered Protein PUMA Does Not Require Particular Residual Structure
[Image: see text] Many cellular proteins are ‘disordered’ in isolation. A subset of these intrinsically disordered proteins (IDPs) can, upon binding another molecule, fold to a well-defined three-dimensional structure. In the structurally heterogeneous, unbound ensemble of these IDPs, conformations...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017604/ https://www.ncbi.nlm.nih.gov/pubmed/24654952 http://dx.doi.org/10.1021/ja4125065 |