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Strained Cycloalkynes as New Protein Sulfenic Acid Traps

[Image: see text] Protein sulfenic acids are formed by the reaction of biologically relevant reactive oxygen species with protein thiols. Sulfenic acid formation modulates the function of enzymes and transcription factors either directly or through the subsequent formation of protein disulfide bonds...

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Detalles Bibliográficos
Autores principales: Poole, Thomas H., Reisz, Julie A., Zhao, Weiling, Poole, Leslie B., Furdui, Cristina M., King, S. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017607/
https://www.ncbi.nlm.nih.gov/pubmed/24724926
http://dx.doi.org/10.1021/ja500364r