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Strained Cycloalkynes as New Protein Sulfenic Acid Traps
[Image: see text] Protein sulfenic acids are formed by the reaction of biologically relevant reactive oxygen species with protein thiols. Sulfenic acid formation modulates the function of enzymes and transcription factors either directly or through the subsequent formation of protein disulfide bonds...
Autores principales: | Poole, Thomas H., Reisz, Julie A., Zhao, Weiling, Poole, Leslie B., Furdui, Cristina M., King, S. Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017607/ https://www.ncbi.nlm.nih.gov/pubmed/24724926 http://dx.doi.org/10.1021/ja500364r |
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