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Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling

Genome‐scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype–phenotype relationship in a mechanistic manner. Here, we evaluated the presence/absence of proteins encoded by 15,841 genes in 27 hepatocellular carcinoma (HCC) patie...

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Detalles Bibliográficos
Autores principales: Agren, Rasmus, Mardinoglu, Adil, Asplund, Anna, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017677/
https://www.ncbi.nlm.nih.gov/pubmed/24646661
http://dx.doi.org/10.1002/msb.145122