Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression

Methylphenidate (MPH) is commonly diverted for recreational use, but the neurobiological consequences of exposure to MPH at high, abused doses are not well defined. Here we show that MPH self-administration in rats increases dopamine transporter (DAT) levels and enhances the potency of MPH and amphe...

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Detalles Bibliográficos
Autores principales: Calipari, Erin S., Ferris, Mark J, Salahpour, Ali, Caron, Marc G., Jones, Sara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017736/
https://www.ncbi.nlm.nih.gov/pubmed/24193139
http://dx.doi.org/10.1038/ncomms3720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017736/
https://www.ncbi.nlm.nih.gov/pubmed/24193139
http://dx.doi.org/10.1038/ncomms3720

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