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QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs

BACKGROUND: Nucleic acids containing guanine tracts can form quadruplex structures via non-Watson-Crick base pairing. Formation of G-quadruplexes is associated with the regulation of important biological functions such as transcription, genetic instability, DNA repair, DNA replication, epigenetic me...

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Detalles Bibliográficos
Autores principales: Frees, Scott, Menendez, Camille, Crum, Matt, Bagga, Paramjeet S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017754/
https://www.ncbi.nlm.nih.gov/pubmed/24885782
http://dx.doi.org/10.1186/1479-7364-8-8