Biological Evaluation of (131)I- and CF750-Labeled Dmab(scFv)-Fc Antibodies for Xenograft Imaging of CD25-Positive Tumors

A Dmab(scFv)-Fc antibody containing the single chain variable fragment of a humanized daclizumab antibody and the Fc fragment of a human IgG1 antibody was produced via recombinant expression in Pichia pastoris. The Dmab(scFv)-Fc antibody forms a dimer in solution, and it specifically binds CD25-posi...

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Detalles Bibliográficos
Autores principales: Fan, Qing, Cai, Huawei, Yang, Hao, Li, Lin, Yuan, Cen, Lu, Xiaofeng, Wan, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017786/
https://www.ncbi.nlm.nih.gov/pubmed/24864244
http://dx.doi.org/10.1155/2014/459676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017786/
https://www.ncbi.nlm.nih.gov/pubmed/24864244
http://dx.doi.org/10.1155/2014/459676

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