IDH1/IDH2 but Not TP53 Mutations Predict Prognosis in Bulgarian Glioblastoma Patients

Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact...

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Detalles Bibliográficos
Autores principales: Stancheva, Gergana, Goranova, Teodora, Laleva, Maria, Kamenova, Margarita, Mitkova, Atanaska, Velinov, Nikolay, Poptodorov, George, Mitev, Vanio, Kaneva, Radka, Gabrovsky, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017788/
https://www.ncbi.nlm.nih.gov/pubmed/24868540
http://dx.doi.org/10.1155/2014/654727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017788/
https://www.ncbi.nlm.nih.gov/pubmed/24868540
http://dx.doi.org/10.1155/2014/654727

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