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An Overview of Y-Family DNA Polymerases and a Case Study of Human DNA Polymerase η
[Image: see text] Y-Family DNA polymerases specialize in translesion synthesis, bypassing damaged bases that would otherwise block the normal progression of replication forks. Y-Family polymerases have unique structural features that allow them to bind damaged DNA and use a modified template base to...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018060/ https://www.ncbi.nlm.nih.gov/pubmed/24716551 http://dx.doi.org/10.1021/bi500019s |