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Role of Tropomodulin’s Leucine Rich Repeat Domain in the Formation of Neurite-like Processes

[Image: see text] Actin dynamics is fundamental for neurite development; monomer depolymerization from pointed ends is rate-limiting in actin treadmilling. Tropomodulins (Tmod) make up a family of actin pointed end-capping proteins. Of the four known isoforms, Tmod1–Tmod3 are expressed in brain cell...

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Detalles Bibliográficos
Autores principales: Guillaud, Laurent, Gray, Kevin T., Moroz, Natalia, Pantazis, Caroline, Pate, Edward, Kostyukova, Alla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018078/
https://www.ncbi.nlm.nih.gov/pubmed/24746171
http://dx.doi.org/10.1021/bi401431k