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Avidity Mechanism of Dendrimer–Folic Acid Conjugates

[Image: see text] Multivalent conjugation of folic acid has been employed to target cells overexpressing folate receptors. Such polymer conjugates have been previously demonstrated to have high avidity to folate binding protein. However, the lack of a monovalent folic acid–polymer material has preve...

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Detalles Bibliográficos
Autores principales: van Dongen, Mallory A., Silpe, Justin E., Dougherty, Casey A., Kanduluru, Ananda Kumar, Choi, Seok Ki, Orr, Bradford G., Low, Philip S., Banaszak Holl, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018099/
https://www.ncbi.nlm.nih.gov/pubmed/24725205
http://dx.doi.org/10.1021/mp5000967