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Synthesis of α,α′-trans-Oxepanes through an Organocatalytic Oxa-conjugate Addition Reaction

[Image: see text] Oxepanes are found in a wide range of natural products; however, they are challenging synthetic targets due to enthalpic and entropic barriers. Organocatalytic oxa-conjugate addition reactions promoted by the gem-disubstituent (Thorpe–Ingold) effect stereoselectively provided α,α′-...

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Detalles Bibliográficos
Autores principales: Lanier, Megan L., Kasper, Amanda C., Kim, Hyoungsu, Hong, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018174/
https://www.ncbi.nlm.nih.gov/pubmed/24724535
http://dx.doi.org/10.1021/ol500773w