Cargando…
4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y(2), P2Y(4), and P2Y(6) Receptors
[Image: see text] Extended N(4)-(3-arylpropyl)oxy derivatives of uridine-5′-triphosphate were synthesized and potently stimulated phospholipase C stimulation in astrocytoma cells expressing G protein-coupled human (h) P2Y receptors (P2YRs) activated by UTP (P2Y(2/4)R) or UDP (P2Y(6)R). The potent P2...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018175/ https://www.ncbi.nlm.nih.gov/pubmed/24712832 http://dx.doi.org/10.1021/jm500367e |