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The Adult Livers of Immunodeficient Mice Support Human Hematopoiesis: Evidence for a Hepatic Mast Cell Population that Develops Early in Human Ontogeny

The liver plays a vital role in hematopoiesis during mammalian prenatal development but its hematopoietic output declines during the perinatal period. Nonetheless, hepatic hematopoiesis is believed to persist into adulthood. We sought to model human adult-liver hematopoiesis by transplantation of fe...

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Detalles Bibliográficos
Autores principales: Muench, Marcus O., Beyer, Ashley I., Fomin, Marina E., Thakker, Rahul, Mulvaney, Usha S., Nakamura, Masato, Suemizu, Hiroshi, Bárcena, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018295/
https://www.ncbi.nlm.nih.gov/pubmed/24819392
http://dx.doi.org/10.1371/journal.pone.0097312