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Chemical Genomic-Based Pathway Analyses for Epidermal Growth Factor-Mediated Signaling in Migrating Cancer Cells

To explore the diversity and consistency of the signaling pathways that regulate tumor cell migration, we chose three human tumor cell lines that migrated after treatment with EGF. We then quantified the effect of fifteen inhibitors on the levels of expression or the phosphorylation levels of nine p...

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Detalles Bibliográficos
Autores principales: Magi, Shigeyuki, Saeki, Yuya, Kasamatsu, Masato, Tashiro, Etsu, Imoto, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018296/
https://www.ncbi.nlm.nih.gov/pubmed/24820097
http://dx.doi.org/10.1371/journal.pone.0096776