Combined isosorbide dinitrate and ibuprofen as a novel therapy for muscular dystrophies: evidence from Phase I studies in healthy volunteers

We designed two Phase I studies that assessed healthy volunteers in order to evaluate the safety and to optimize the dosing of the combination of the drugs isosorbide dinitrate, a nitric oxide donor, and ibuprofen, a nonsteroidal antiinflammatory drug. We designed these studies with the aim of desig...

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Detalles Bibliográficos
Autores principales: Cossu, Maria Vittoria, Cattaneo, Dario, Fucile, Serena, Pellegrino, Paolo, Baldelli, Sara, Cozzi, Valeria, Capetti, Amedeo, Clementi, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018313/
https://www.ncbi.nlm.nih.gov/pubmed/24851040
http://dx.doi.org/10.2147/DDDT.S58803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018313/
https://www.ncbi.nlm.nih.gov/pubmed/24851040
http://dx.doi.org/10.2147/DDDT.S58803

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