Histone Deacetylase Inhibitor Treatment Increases Coronary t-PA Release in a Porcine Ischemia Model

BACKGROUND: The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control. OBJECTIVES: The study aimed to test if in vivo pharmacological intervention by valproic acid treatment would lead to increase in ti...

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Detalles Bibliográficos
Autores principales: Svennerholm, Kristina, Bergh, Niklas, Larsson, Pia, Jern, Sverker, Johansson, Göran, Biber, Björn, Haney, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018339/
https://www.ncbi.nlm.nih.gov/pubmed/24818610
http://dx.doi.org/10.1371/journal.pone.0097260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018339/
https://www.ncbi.nlm.nih.gov/pubmed/24818610
http://dx.doi.org/10.1371/journal.pone.0097260

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