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Epigenetic Characterization of the Growth Hormone Gene Identifies SmcHD1 as a Regulator of Autosomal Gene Clusters

Regulatory elements for the mouse growth hormone (GH) gene are located distally in a putative locus control region (LCR) in addition to key elements in the promoter proximal region. The role of promoter DNA methylation for GH gene regulation is not well understood. Pit-1 is a POU transcription facto...

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Detalles Bibliográficos
Autores principales: Massah, Shabnam, Hollebakken, Robert, Labrecque, Mark P., Kolybaba, Addie M., Beischlag, Timothy V., Prefontaine, Gratien G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018343/
https://www.ncbi.nlm.nih.gov/pubmed/24818964
http://dx.doi.org/10.1371/journal.pone.0097535