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Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up-Regulates OPG in an Experimental Periodontitis Model

AIMS: The aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear factor κB (RANK), osteoprotegerin (OPG), cyclooxygena...

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Detalles Bibliográficos
Autores principales: de Araújo, Aurigena Antunes, Varela, Hugo, Brito, Gerly Anne de Castro, de Medeiros, Caroline Addison Carvalho Xavier, Araújo, Lorena de Souza, do Nascimento, José Heriberto Oliveira, de Araújo Júnior, Raimundo Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018354/
https://www.ncbi.nlm.nih.gov/pubmed/24819928
http://dx.doi.org/10.1371/journal.pone.0096750