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Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up-Regulates OPG in an Experimental Periodontitis Model
AIMS: The aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear factor κB (RANK), osteoprotegerin (OPG), cyclooxygena...
Autores principales: | de Araújo, Aurigena Antunes, Varela, Hugo, Brito, Gerly Anne de Castro, de Medeiros, Caroline Addison Carvalho Xavier, Araújo, Lorena de Souza, do Nascimento, José Heriberto Oliveira, de Araújo Júnior, Raimundo Fernandes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018354/ https://www.ncbi.nlm.nih.gov/pubmed/24819928 http://dx.doi.org/10.1371/journal.pone.0096750 |
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