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Stimulus-Selective Regulation of Human Mast Cell Gene Expression, Degranulation and Leukotriene Production by Fluticasone and Salmeterol

Despite the fact that glucocorticoids and long acting beta agonists are effective treatments for asthma, their effects on human mast cells (MC) appear to be modest. Although MC are one of the major effector cells in the underlying inflammatory reactions associated with asthma, their regulation by th...

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Detalles Bibliográficos
Autores principales: Catalli, Adriana, Karpov, Victor, Erdos, Levente E., Tancowny, Brian P., Schleimer, Robert P., Kulka, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018391/
https://www.ncbi.nlm.nih.gov/pubmed/24819142
http://dx.doi.org/10.1371/journal.pone.0096891