Genetic Association Study of Adiposity and Melanocortin-4 Receptor (MC4R) Common Variants: Replication and Functional Characterization of Non-Coding Regions

Common genetic variants 3′ of MC4R within two large linkage disequilibrium (LD) blocks spanning 288 kb have been associated with common and rare forms of obesity. This large association region has not been refined and the relevant DNA segments within the association region have not been identified....

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Detalles Bibliográficos
Autores principales: Evans, Daniel S., Calton, Melissa A., Kim, Mee J., Kwok, Pui-Yan, Miljkovic, Iva, Harris, Tamara, Koster, Annemarie, Liu, Yongmei, Tranah, Gregory J., Ahituv, Nadav, Hsueh, Wen-Chi, Vaisse, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018404/
https://www.ncbi.nlm.nih.gov/pubmed/24820477
http://dx.doi.org/10.1371/journal.pone.0096805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018404/
https://www.ncbi.nlm.nih.gov/pubmed/24820477
http://dx.doi.org/10.1371/journal.pone.0096805

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