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Genetic Association Study of Adiposity and Melanocortin-4 Receptor (MC4R) Common Variants: Replication and Functional Characterization of Non-Coding Regions
Common genetic variants 3′ of MC4R within two large linkage disequilibrium (LD) blocks spanning 288 kb have been associated with common and rare forms of obesity. This large association region has not been refined and the relevant DNA segments within the association region have not been identified....
Autores principales: | Evans, Daniel S., Calton, Melissa A., Kim, Mee J., Kwok, Pui-Yan, Miljkovic, Iva, Harris, Tamara, Koster, Annemarie, Liu, Yongmei, Tranah, Gregory J., Ahituv, Nadav, Hsueh, Wen-Chi, Vaisse, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018404/ https://www.ncbi.nlm.nih.gov/pubmed/24820477 http://dx.doi.org/10.1371/journal.pone.0096805 |
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