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Hexicon 2: Automated Processing of Hydrogen-Deuterium Exchange Mass Spectrometry Data with Improved Deuteration Distribution Estimation

Hydrogen–deuterium exchange (HDX) experiments analyzed by mass spectrometry (MS) provide information about the dynamics and the solvent accessibility of protein backbone amide hydrogen atoms. Continuous improvement of MS instrumentation has contributed to the increasing popularity of this method; ho...

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Detalles Bibliográficos
Autores principales: Lindner, Robert, Lou, Xinghua, Reinstein, Jochen, Shoeman, Robert L, Hamprecht, Fred A, Winkler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018513/
https://www.ncbi.nlm.nih.gov/pubmed/24676893
http://dx.doi.org/10.1007/s13361-014-0850-y