OX(1) and OX(2) orexin/hypocretin receptor pharmacogenetics

Orexin/hypocretin peptide mutations are rare in humans. Even though human narcolepsy is associated with orexin deficiency, this is only extremely rarely due to mutations in the gene coding prepro-orexin, the precursor for both orexin peptides. In contrast, coding and non-coding variants of the OX(1)...

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Detalles Bibliográficos
Autores principales: Thompson, Miles D., Xhaard, Henri, Sakurai, Takeshi, Rainero, Innocenzo, Kukkonen, Jyrki P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018553/
https://www.ncbi.nlm.nih.gov/pubmed/24834023
http://dx.doi.org/10.3389/fnins.2014.00057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018553/
https://www.ncbi.nlm.nih.gov/pubmed/24834023
http://dx.doi.org/10.3389/fnins.2014.00057

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