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CaMKII-dependent responses to ischemia and reperfusion challenges in the heart

Ischemic heart disease is a leading cause of death, and there is considerable imperative to identify effective therapeutic interventions. Cardiomyocyte Ca(2+) overload is a major cause of ischemia and reperfusion injury, initiating a cascade of events culminating in cardiomyocyte death, myocardial d...

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Detalles Bibliográficos
Autores principales: Bell, James R., Vila-Petroff, Martin, Delbridge, Lea M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018566/
https://www.ncbi.nlm.nih.gov/pubmed/24834054
http://dx.doi.org/10.3389/fphar.2014.00096