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Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease

Studying human vascular disease in conventional cell cultures and in animal models does not effectively mimic the complex vascular microenvironment and may not accurately predict vascular responses in humans. We utilized a microfluidic device to recapitulate both shear stress and O(2) levels in heal...

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Detalles Bibliográficos
Autores principales: Abaci, Hasan Erbil, Shen, Yu-I, Tan, Scott, Gerecht, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018609/
https://www.ncbi.nlm.nih.gov/pubmed/24818558
http://dx.doi.org/10.1038/srep04951