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Pericentromere tension is self-regulated by spindle structure in metaphase

During cell division, a mitotic spindle is built by the cell and acts to align and stretch duplicated sister chromosomes before their ultimate segregation into daughter cells. Stretching of the pericentromeric chromatin during metaphase is thought to generate a tension-based signal that promotes pro...

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Detalles Bibliográficos
Autores principales: Chacón, Jeremy M., Mukherjee, Soumya, Schuster, Breanna M., Clarke, Duncan J., Gardner, Melissa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018788/
https://www.ncbi.nlm.nih.gov/pubmed/24821839
http://dx.doi.org/10.1083/jcb.201312024