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Pericentromere tension is self-regulated by spindle structure in metaphase
During cell division, a mitotic spindle is built by the cell and acts to align and stretch duplicated sister chromosomes before their ultimate segregation into daughter cells. Stretching of the pericentromeric chromatin during metaphase is thought to generate a tension-based signal that promotes pro...
Autores principales: | Chacón, Jeremy M., Mukherjee, Soumya, Schuster, Breanna M., Clarke, Duncan J., Gardner, Melissa K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018788/ https://www.ncbi.nlm.nih.gov/pubmed/24821839 http://dx.doi.org/10.1083/jcb.201312024 |
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