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Ciliary transition zone activation of phospho-Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

Primary cilia are displayed during the G(0)/G(1) phase of many cell types. Cilia are reabsorbed as cells prepare to re-enter the cell cycle, but the causal and molecular link between these two cellular events remains unclear. We show that phospho(T94)Tctex-1 is recruited to ciliary transition zones...

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Detalles Bibliográficos
Autores principales: Li, Aiqun, Saito, Masaki, Chuang, Jen-Zen, Tseng, Yun-Yu, Dedesma, Carlos, Tomizawa, Kazuhito, Kaitsuka, Taku, Sung, Ching-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018803/
https://www.ncbi.nlm.nih.gov/pubmed/21394082
http://dx.doi.org/10.1038/ncb2218