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Exploring the Biological and Chemical Complexity of the Ligases

Using a novel method to map and cluster chemical reactions, we have re-examined the chemistry of the ligases [Enzyme Commission (EC) Class 6] and their associated protein families in detail. The type of bond formed by the ligase can be automatically extracted from the equation of the reaction, repli...

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Detalles Bibliográficos
Autores principales: Holliday, Gemma L., Rahman, Syed Asad, Furnham, Nicholas, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018984/
https://www.ncbi.nlm.nih.gov/pubmed/24657765
http://dx.doi.org/10.1016/j.jmb.2014.03.008