Localization of hepatocyte nuclear factor‐4α in the nucleolus and nucleus is regulated by its C‐terminus

Aims/Introduction:  Mutations in hepatocyte nuclear factor‐4α (HNF4α) lead to various diseases, among which C‐terminal deletions of HNF4α are exclusively responsible for maturity onset diabetes of the young 1 (MODY1). MODY is an autosomal dominant disease characterized by a primary defect in insulin...

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Detalles Bibliográficos
Autores principales: Ogata, Makiko, Awaji, Takeo, Iwasaki, Naoko, Fujimaki, Risa, Takizawa, Miho, Maruyama, Kei, Bell, Graeme I, Iwamoto, Yasuhiko, Uchigata, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019245/
https://www.ncbi.nlm.nih.gov/pubmed/24843605
http://dx.doi.org/10.1111/j.2040-1124.2012.00210.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019245/
https://www.ncbi.nlm.nih.gov/pubmed/24843605
http://dx.doi.org/10.1111/j.2040-1124.2012.00210.x

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