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Localization of hepatocyte nuclear factor‐4α in the nucleolus and nucleus is regulated by its C‐terminus
Aims/Introduction: Mutations in hepatocyte nuclear factor‐4α (HNF4α) lead to various diseases, among which C‐terminal deletions of HNF4α are exclusively responsible for maturity onset diabetes of the young 1 (MODY1). MODY is an autosomal dominant disease characterized by a primary defect in insulin...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019245/ https://www.ncbi.nlm.nih.gov/pubmed/24843605 http://dx.doi.org/10.1111/j.2040-1124.2012.00210.x |