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Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4‐associated oxidative stress in diabetic hamsters
Aims/Introduction: Diabetic cardiomyopathy entails the cardiac injury induced by diabetes, independent of vascular disease or hypertension. Despite numerous experimental studies and clinical trials, the pathogenesis of diabetic cardiomyopathy remains elusive. Here, we report that chymase, an immedi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019255/ https://www.ncbi.nlm.nih.gov/pubmed/24843590 http://dx.doi.org/10.1111/j.2040-1124.2012.00202.x |