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Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4‐associated oxidative stress in diabetic hamsters

Aims/Introduction: Diabetic cardiomyopathy entails the cardiac injury induced by diabetes, independent of vascular disease or hypertension. Despite numerous experimental studies and clinical trials, the pathogenesis of diabetic cardiomyopathy remains elusive. Here, we report that chymase, an immedi...

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Detalles Bibliográficos
Autores principales:	Maeda, Yasutaka, Inoguchi, Toyoshi, Takei, Ryoko, Hendarto, Hari, Ide, Makoto, Inoue, Tomoaki, Kobayashi, Kunihisa, Urata, Hidenori, Nishiyama, Akira, Takayanagi, Ryoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019255/ https://www.ncbi.nlm.nih.gov/pubmed/24843590 http://dx.doi.org/10.1111/j.2040-1124.2012.00202.x

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