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KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

The functional properties of KCNQ1 channels are highly dependent on associated KCNE β subunits. Mutations in KCNQ1 or KCNE subunits can cause congenital channelopathies, such as deafness, cardiac arrhythmias, and epilepsy. The mechanism by which KCNE1 beta subunits slow the kinetics of KCNQ1 channel...

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Detalles Bibliográficos
Autores principales: Barro-Soria, Rene, Rebolledo, Santiago, Liin, Sara I., Perez, Marta E., Sampson, Kevin J., Kass, Robert S., Larsson, H Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019390/
https://www.ncbi.nlm.nih.gov/pubmed/24769622
http://dx.doi.org/10.1038/ncomms4750