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Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β

Transforming growth factor-β (TGF-β) ligands activate Smad-mediated and noncanonical signaling pathways in a cell context–dependent manner. Localization of signaling receptors to distinct membrane domains is a potential source of signaling output diversity. The tumor suppressor/endocytic adaptor pro...

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Detalles Bibliográficos
Autores principales: Shapira, Keren E., Hirschhorn, Tal, Barzilay, Lior, Smorodinsky, Nechama I., Henis, Yoav I., Ehrlich, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019493/
https://www.ncbi.nlm.nih.gov/pubmed/24648493
http://dx.doi.org/10.1091/mbc.E13-09-0537