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MicroRNA-27a Modulates HCV Infection in Differentiated Hepatocyte-Like Cells from Adipose Tissue-Derived Mesenchymal Stem Cells

BACKGROUND AND AIMS: Despite the discovery of hepatitis C virus (HCV) entry factor, the mechanism by which it is regulated by miRNAs remains unclear. Adipose tissue-derived human mesenchymal stem cells (AT-hMSCs) have been widely used for differentiated hepatocyte-like cells (DHCs). Here, we establi...

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Detalles Bibliográficos
Autores principales: Choi, Jung Eun, Hur, Wonhee, Kim, Jung-Hee, Li, Tian Zhu, Lee, Eun Byul, Lee, Sung Won, Kang, Wonseok, Shin, Eui-Cheol, Wakita, Takaji, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019502/
https://www.ncbi.nlm.nih.gov/pubmed/24824429
http://dx.doi.org/10.1371/journal.pone.0091958