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Monocytes from Chronic HBV Patients React In Vitro to HBsAg and TLR by Producing Cytokines Irrespective of Stage of Disease

Individuals who are chronically infected with the hepatitis B virus (HBV) are highly heterogenous with respect to serum levels of HBV DNA, HBV particles and viral proteins. Since circulating leukocytes, such as monocytes, are constantly exposed to these viral components, it is likely that the functi...

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Detalles Bibliográficos
Autores principales: Boltjes, Arjan, Groothuismink, Zwier M., van Oord, Gertine W., Janssen, Harry L. A., Woltman, Andrea M., Boonstra, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019549/
https://www.ncbi.nlm.nih.gov/pubmed/24824830
http://dx.doi.org/10.1371/journal.pone.0097006