Potent and Specific Inhibition of Glycosidases by Small Artificial Binding Proteins (Affitins)

Glycosidases are associated with various human diseases. The development of efficient and specific inhibitors may provide powerful tools to modulate their activity. However, achieving high selectivity is a major challenge given that glycosidases with different functions can have similar enzymatic me...

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Detalles Bibliográficos
Autores principales: Correa, Agustín, Pacheco, Sabino, Mechaly, Ariel E., Obal, Gonzalo, Béhar, Ghislaine, Mouratou, Barbara, Oppezzo, Pablo, Alzari, Pedro M., Pecorari, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019568/
https://www.ncbi.nlm.nih.gov/pubmed/24823716
http://dx.doi.org/10.1371/journal.pone.0097438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019568/
https://www.ncbi.nlm.nih.gov/pubmed/24823716
http://dx.doi.org/10.1371/journal.pone.0097438

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