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Activation of c-Met and Upregulation of CD44 Expression Are Associated with the Metastatic Phenotype in the Colorectal Cancer Liver Metastasis Model

BACKGROUND: Liver metastasis is the most common cause of death in patients with colorectal cancer. Despite extensive research into the biology of cancer progression, the molecular mechanisms that drive colorectal cancer metastasis are not well characterized. METHODS: HT29 LM1, HT29 LM2, HT29 LM3 cel...

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Detalles Bibliográficos
Autores principales: Elliott, Victoria A., Rychahou, Piotr, Zaytseva, Yekaterina Y., Evers, B. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019574/
https://www.ncbi.nlm.nih.gov/pubmed/24823486
http://dx.doi.org/10.1371/journal.pone.0097432