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Biochemical Analysis of DNA Polymerase η Fidelity in the Presence of Replication Protein A
DNA polymerase η (pol η) synthesizes across from damaged DNA templates in order to prevent deleterious consequences like replication fork collapse and double-strand breaks. This process, termed translesion synthesis (TLS), is an overall positive for the cell, as cells deficient in pol η display high...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019591/ https://www.ncbi.nlm.nih.gov/pubmed/24824831 http://dx.doi.org/10.1371/journal.pone.0097382 |