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Efficiently engineered cell sheet using a complex of polyethylenimine–alginate nanocomposites plus bone morphogenetic protein 2 gene to promote new bone formation

Regeneration of large bone defects is a common clinical problem. Recently, stem cell sheet has been an emerging strategy in bone tissue engineering. To enhance the osteogenic potential of stem cell sheet, we fabricated bone morphogenetic protein 2 (BMP-2) gene-engineered cell sheet using a complex o...

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Detalles Bibliográficos
Autores principales: Jin, Han, Zhang, Kai, Qiao, Chunyan, Yuan, Anliang, Li, Daowei, Zhao, Liang, Shi, Ce, Xu, Xiaowei, Ni, Shilei, Zheng, Changyu, Liu, Xiaohua, Yang, Bai, Sun, Hongchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019610/
https://www.ncbi.nlm.nih.gov/pubmed/24855355
http://dx.doi.org/10.2147/IJN.S60937