Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats

Mammalian skeletal muscles exhibit age-related adaptive and pathological remodeling. Several muscles in particular undergo progressive atrophy and degeneration beyond median lifespan. To better understand myocellular responses to aging, we used semi-quantitative global metabolomic profiling to chara...

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Detalles Bibliográficos
Autores principales: Garvey, Sean M., Dugle, Janis E., Kennedy, Adam D., McDunn, Jonathan E., Kline, William, Guo, Lining, Guttridge, Denis C., Pereira, Suzette L., Edens, Neile K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019835/
https://www.ncbi.nlm.nih.gov/pubmed/24652515
http://dx.doi.org/10.1007/s10522-014-9492-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019835/
https://www.ncbi.nlm.nih.gov/pubmed/24652515
http://dx.doi.org/10.1007/s10522-014-9492-5

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