Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in growth pathways

Protein phosphorylation homoeostasis is tightly controlled and pathological conditions are caused by subtle alterations of the cell phosphorylation profile. Altered levels of kinase activities have already been associated to specific diseases. Less is known about the impact of phosphatases, the enzy...

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Detalles Bibliográficos
Autores principales: Sacco, Francesca, Boldt, Karsten, Calderone, Alberto, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Ueffing, Marius, Cesareni, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019850/
https://www.ncbi.nlm.nih.gov/pubmed/24847354
http://dx.doi.org/10.3389/fgene.2014.00115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019850/
https://www.ncbi.nlm.nih.gov/pubmed/24847354
http://dx.doi.org/10.3389/fgene.2014.00115

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