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Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in growth pathways
Protein phosphorylation homoeostasis is tightly controlled and pathological conditions are caused by subtle alterations of the cell phosphorylation profile. Altered levels of kinase activities have already been associated to specific diseases. Less is known about the impact of phosphatases, the enzy...
Autores principales: | Sacco, Francesca, Boldt, Karsten, Calderone, Alberto, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Ueffing, Marius, Cesareni, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019850/ https://www.ncbi.nlm.nih.gov/pubmed/24847354 http://dx.doi.org/10.3389/fgene.2014.00115 |
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