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Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4(+)IL17(+) response

BACKGROUND: We tested the hypothesis that a novel vaccine developed from autologous dendritic cells (DC) loaded with cells from a unique allogeneic brain tumor cell line (GBM6-AD) would be well-tolerated and would generate an immune response. METHOD: Patients with recurrent primary brain tumors unde...

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Detalles Bibliográficos
Autores principales: Olin, Michael R, Low, Walter, McKenna, David H, Haines, Stephen J, Dahlheimer, Tambra, Nascene, David, Gustafson, Michael P, Dietz, Allan B, Clark, H Brent, Chen, Wei, Blazar, Bruce, Ohlfest, John R, Moertel, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019901/
https://www.ncbi.nlm.nih.gov/pubmed/24829761
http://dx.doi.org/10.1186/2051-1426-2-4